<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>10</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Abernethy, J.</style></author><author><style face="normal" font="default" size="100%">Sartore, L.</style></author><author><style face="normal" font="default" size="100%">Benecha, H.</style></author><author><style face="normal" font="default" size="100%">Spiegelman, C.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Estimation of Capture Probabilities by Accounting for Sample Designs</style></title><secondary-title><style face="normal" font="default" size="100%">JSM 2017</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Agriculture</style></keyword><keyword><style  face="normal" font="default" size="100%">CaptureRecapture</style></keyword><keyword><style  face="normal" font="default" size="100%">Estimation</style></keyword><keyword><style  face="normal" font="default" size="100%">government</style></keyword><keyword><style  face="normal" font="default" size="100%">NASS</style></keyword><keyword><style  face="normal" font="default" size="100%">Research</style></keyword><keyword><style  face="normal" font="default" size="100%">SampleDesigns</style></keyword><keyword><style  face="normal" font="default" size="100%">Weights</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">Submitted</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.niss.org/sites/default/files/Abernethy_Capture_Probs_20170920.pdf</style></url></web-urls></urls><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The United States Department of Agriculture’s (USDA’s) National Agricultural Statistics Service (NASS) conducts the Census of Agriculture every five years to estimate the number of U.S. farms, as well as other agriculturally related population totals. NASS applies a Dual-System Estimation (DSE) methodology on data collected from the Census and the June Area Survey (JAS) to estimate the number of farms in the U.S.. Traditional multinomial-based capture-recapture methodology requires a model to estimate the probability of capture for every captured operation on either survey. Of course, the selection probabilities associated with the JAS area frame design are different from those associated with the Census. Such a difference makes it difficult to compute the exact JAS selection probabilities for farm records captured only by the Census. For this reason, we propose and compare three methods for estimating the overall capture probability. The first two methods involve approximating the JAS selection probabilities and the third conditions them out. We compare these three techniques to investigate their precision through a simulation study.&lt;/p&gt;
</style></abstract><custom1><style face="normal" font="default" size="100%">&lt;p&gt;In Proceedings of the Government Statistics Section, JSM 2017. Download&amp;nbsp;https://www.niss.org/sites/default/files/Abernethy_Capture_Probs_20170920.pdf&lt;/p&gt;
</style></custom1></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>10</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Benecha, H.</style></author><author><style face="normal" font="default" size="100%">Abreu, D.</style></author><author><style face="normal" font="default" size="100%">Abernethy, J.</style></author><author><style face="normal" font="default" size="100%">Sartore, L.</style></author><author><style face="normal" font="default" size="100%">Young, L. Y.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%"> Evaluation of a New Approach for Estimating the Number of U.S. Farms</style></title><secondary-title><style face="normal" font="default" size="100%">JSM 2017</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Agriculture</style></keyword><keyword><style  face="normal" font="default" size="100%">Area-frame</style></keyword><keyword><style  face="normal" font="default" size="100%">BigData</style></keyword><keyword><style  face="normal" font="default" size="100%">Capture-Recapture</style></keyword><keyword><style  face="normal" font="default" size="100%">List Frame</style></keyword><keyword><style  face="normal" font="default" size="100%">Logistic Regression</style></keyword><keyword><style  face="normal" font="default" size="100%">Misclassification Error</style></keyword><keyword><style  face="normal" font="default" size="100%">NASS</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">Submitted</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.niss.org/sites/default/files/Benecha_Estim_Farms_20170929.pdf</style></url></web-urls></urls><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;USDA’s National Agricultural Statistics Service (NASS) employs the June Area Survey (JAS) to produce annual&amp;nbsp;estimates of U.S. farm numbers. The JAS is an area-frame-based survey conducted every year during the first two&amp;nbsp;weeks of June. NASS also publishes an independent estimate of the number of farms from the quinquennial Census&amp;nbsp;of Agriculture. Studies conducted by NASS have shown that farm number estimates from the JAS can be biased,&amp;nbsp;mainly due to misclassification of agricultural tracts during the pre-screening and data collection processes. To adjust&amp;nbsp;for the bias, NASS has developed a capture-recapture model that uses NASS’s list frame as the second sample, where&amp;nbsp;estimation is performed based on records in the JAS with matches in the list frame. In the current paper, we describe&amp;nbsp;an alternative capture-recapture approach that uses all available data from the JAS and the Census of Agriculture to&amp;nbsp;correct for biases due to misclassification and to produce more stable farm number estimates.&lt;/p&gt;
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Survey Research Methods Section. Alexandria, VA: American Statistical Association.</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2016</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://ww2.amstat.org/MembersOnly/proceedings/2016/data/assets/pdf/389784.pdf</style></url></web-urls></urls><language><style face="normal" font="default" size="100%">eng</style></language><section><style face="normal" font="default" size="100%">3591-3605 </style></section></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Susan Abbatiello</style></author><author><style face="normal" font="default" size="100%">Birgit Schilling</style></author><author><style face="normal" font="default" size="100%">D.R. Mani</style></author><author><style face="normal" font="default" size="100%">L.I. Shilling</style></author><author><style face="normal" font="default" size="100%">S.C. Hall</style></author><author><style face="normal" font="default" size="100%">B. McLean</style></author><author><style face="normal" font="default" size="100%">M. Albetolle</style></author><author><style face="normal" font="default" size="100%">S. Allen</style></author><author><style face="normal" font="default" size="100%">M. Burgess</style></author><author><style face="normal" font="default" size="100%">M.P. Cusack</style></author><author><style face="normal" font="default" size="100%">M Gosh</style></author><author><style face="normal" font="default" size="100%">V Hedrick</style></author><author><style face="normal" font="default" size="100%">J.M. Held</style></author><author><style face="normal" font="default" size="100%">H.D. Inerowicz</style></author><author><style face="normal" font="default" size="100%">A. Jackson</style></author><author><style face="normal" font="default" size="100%">H. Keshishian</style></author><author><style face="normal" font="default" size="100%">C.R. Kinsinger</style></author><author><style face="normal" font="default" size="100%">Lyssand, JS</style></author><author><style face="normal" font="default" size="100%">Makowski L</style></author><author><style face="normal" font="default" size="100%">Mesri M</style></author><author><style face="normal" font="default" size="100%">Rodriguez H</style></author><author><style face="normal" font="default" size="100%">Rudnick P</style></author><author><style face="normal" font="default" size="100%">Sadowski P</style></author><author><style face="normal" font="default" size="100%">Nell Sedransk</style></author><author><style face="normal" font="default" size="100%">Shaddox K</style></author><author><style face="normal" font="default" size="100%">Skates SJ</style></author><author><style face="normal" font="default" size="100%">Kuhn E</style></author><author><style face="normal" font="default" size="100%">Smith D</style></author><author><style face="normal" font="default" size="100%">Whiteaker, JR</style></author><author><style face="normal" font="default" size="100%">Whitwell C</style></author><author><style face="normal" font="default" size="100%">Zhang S</style></author><author><style face="normal" font="default" size="100%">Borchers CH</style></author><author><style face="normal" font="default" size="100%">Fisher SJ</style></author><author><style face="normal" font="default" size="100%">Gibson BW</style></author><author><style face="normal" font="default" size="100%">Liebler DC</style></author><author><style face="normal" font="default" size="100%">M.J. McCoss</style></author><author><style face="normal" font="default" size="100%">Neubert TA</style></author><author><style face="normal" font="default" size="100%">Paulovich AG</style></author><author><style face="normal" font="default" size="100%">Regnier FE</style></author><author><style face="normal" font="default" size="100%">Tempst, P</style></author><author><style face="normal" font="default" size="100%">Carr, SA</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma.</style></title><secondary-title><style face="normal" font="default" size="100%">Molecular Cell Proteomics</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">09/2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">2357-74</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;There is an increasing need in biology and clinical medicine to robustly and reliably measure tens to hundreds of peptides and proteins in clinical and biological samples with high sensitivity, specificity, reproducibility, and repeatability. Previously, we demonstrated that LC-MRM-MS with isotope dilution has suitable performance for quantitative measurements of small numbers of relatively abundant proteins in human plasma and that the resulting assays can be transferred across laboratories while maintaining high reproducibility and quantitative precision. Here, we significantly extend that earlier work, demonstrating that 11 laboratories using 14 LC-MS systems can develop, determine analytical figures of merit, and apply highly multiplexed MRM-MS assays targeting 125 peptides derived from 27 cancer-relevant proteins and seven control proteins to precisely and reproducibly measure the analytes in human plasma. To ensure consistent generation of high quality data, we incorporated a system suitability protocol (SSP) into our experimental design. The SSP enabled real-time monitoring of LC-MRM-MS performance during assay development and implementation, facilitating early detection and correction of chromatographic and instrumental problems. Low to subnanogram/ml sensitivity for proteins in plasma was achieved by one-step immunoaffinity depletion of 14 abundant plasma proteins prior to analysis. Median intra- and interlaboratory reproducibility was &amp;lt;20%, sufficient for most biological studies and candidate protein biomarker verification. Digestion recovery of peptides was assessed and quantitative accuracy improved using heavy-isotope-labeled versions of the proteins as internal standards. Using the highly multiplexed assay, participating laboratories were able to precisely and reproducibly determine the levels of a series of analytes in blinded samples used to simulate an interlaboratory clinical study of patient samples. Our study further establishes that LC-MRM-MS using stable isotope dilution, with appropriate attention to analytical validation and appropriate quality control measures, enables sensitive, specific, reproducible, and quantitative measurements of proteins and peptides in complex biological matrices such as plasma.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">9</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>47</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">A. F. Karr</style></author><author><style face="normal" font="default" size="100%">Z. He</style></author><author><style face="normal" font="default" size="100%">M. P. Cohen</style></author><author><style face="normal" font="default" size="100%">D. Battle</style></author><author><style face="normal" font="default" size="100%">D. L. Achorn</style></author><author><style face="normal" font="default" size="100%">A. D. McKay</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Construction of replicate weights for Project TALENT</style></title><secondary-title><style face="normal" font="default" size="100%">JSM Proceedings, Section on Survey Research Methods 2013</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2013</style></year></dates><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Abbatiello, S.</style></author><author><style face="normal" font="default" size="100%">Feng, X.</style></author><author><style face="normal" font="default" size="100%">Sedransk, N.</style></author><author><style face="normal" font="default" size="100%">Mani, DR</style></author><author><style face="normal" font="default" size="100%">Schilling, B</style></author><author><style face="normal" font="default" size="100%">Maclean, B</style></author><author><style face="normal" font="default" size="100%">Zimmerman, LJ</style></author><author><style face="normal" font="default" size="100%">Cusack, MP</style></author><author><style face="normal" font="default" size="100%">Hall, SC</style></author><author><style face="normal" font="default" size="100%">Addona, T</style></author><author><style face="normal" font="default" size="100%">Allen, S</style></author><author><style face="normal" font="default" size="100%">Dodder, NG</style></author><author><style face="normal" font="default" size="100%">Ghosh, M</style></author><author><style face="normal" font="default" size="100%">Held, JM</style></author><author><style face="normal" font="default" size="100%">Hedrick, V</style></author><author><style face="normal" font="default" size="100%">Inerowicz, HD</style></author><author><style face="normal" font="default" size="100%">Jackson, A</style></author><author><style face="normal" font="default" size="100%">Keshishian, H</style></author><author><style face="normal" font="default" size="100%">Kim, JW</style></author><author><style face="normal" font="default" size="100%">Lyssand, JS</style></author><author><style face="normal" font="default" size="100%">Riley, CP</style></author><author><style face="normal" font="default" size="100%">Rudnick, P</style></author><author><style face="normal" font="default" size="100%">Sadowski, P</style></author><author><style face="normal" font="default" size="100%">Shaddox, K</style></author><author><style face="normal" font="default" size="100%">Smith, D</style></author><author><style face="normal" font="default" size="100%">Tomazela, D</style></author><author><style face="normal" font="default" size="100%">Wahlander, A</style></author><author><style face="normal" font="default" size="100%">Waldemarson, S</style></author><author><style face="normal" font="default" size="100%">Whitwell, CA</style></author><author><style face="normal" font="default" size="100%">You, J</style></author><author><style face="normal" font="default" size="100%">Zhang, S</style></author><author><style face="normal" font="default" size="100%">Kinsinger, CR</style></author><author><style face="normal" font="default" size="100%">Mesri, M</style></author><author><style face="normal" font="default" size="100%">Rodriguez, H</style></author><author><style face="normal" font="default" size="100%">Borchers, CH</style></author><author><style face="normal" font="default" size="100%">Buck, C</style></author><author><style face="normal" font="default" size="100%">Fisher, SJ</style></author><author><style face="normal" font="default" size="100%">Gibson, BW</style></author><author><style face="normal" font="default" size="100%">Liebler, D</style></author><author><style face="normal" font="default" size="100%">Maccoss, M</style></author><author><style face="normal" font="default" size="100%">Neubert, TA</style></author><author><style face="normal" font="default" size="100%">Paulovich, A</style></author><author><style face="normal" font="default" size="100%">Regnier, F</style></author><author><style face="normal" font="default" size="100%">Skates, SJ</style></author><author><style face="normal" font="default" size="100%">Tempst, P</style></author><author><style face="normal" font="default" size="100%">Wang, M</style></author><author><style face="normal" font="default" size="100%">Carr, SA</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Design, Implementation and Multisite Evaluation of a System Suitability Protocol for the Quantitative Assessment of Instrument Performance in Liquid Chromatography-Multiple Reaction Monitoring-MS (LC-MRM-MS)</style></title><secondary-title><style face="normal" font="default" size="100%">Molecular and Cellular Proteomics</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2013</style></year></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">2623-2639</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Multiple reaction monitoring (MRM) mass spectrometry coupled with stable isotope dilution (SID) and liquid chromatography (LC) is increasingly used in biological and clinical studies for precise and reproducible quantification of peptides and proteins in complex sample matrices. Robust LC-SID-MRM-MS-based assays that can be replicated across laboratories and ultimately in clinical laboratory settings require standardized protocols to demonstrate that the analysis platforms are performing adequately. We developed a system suitability protocol (SSP), which employs a predigested mixture of six proteins, to facilitate performance evaluation of LC-SID-MRM-MS instrument platforms, configured with nanoflow-LC systems interfaced to triple quadrupole mass spectrometers. The SSP was designed for use with low multiplex analyses as well as high multiplex approaches when software-driven scheduling of data acquisition is required. Performance was assessed by monitoring of a range of chromatographic and mass spectrometric metrics including peak width, chromatographic resolution, peak capacity, and the variability in peak area and analyte retention time (RT) stability. The SSP, which was evaluated in 11 laboratories on a total of 15 different instruments, enabled early diagnoses of LC and MS anomalies that indicated suboptimal LC-MRM-MS performance. The observed range in variation of each of the metrics scrutinized serves to define the criteria for optimized LC-SID-MRM-MS platforms for routine use, with pass/fail criteria for system suitability performance measures defined as peak area coefficient of variation &amp;lt;0.15, peak width coefficient of variation &amp;lt;0.15, standard deviation of RT &amp;lt;0.15 min (9 s), and the RT drift &amp;lt;0.5min (30 s). The deleterious effect of a marginally performing LC-SID-MRM-MS system on the limit of quantification (LOQ) in targeted quantitative assays illustrates the use and need for a SSP to establish robust and reliable system performance. Use of a SSP helps to ensure that analyte quantification measurements can be replicated with good precision within and across multiple laboratories and should facilitate more widespread use of MRM-MS technology by the basic biomedical and clinical laboratory research communities.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hughes-Oliver JM</style></author><author><style face="normal" font="default" size="100%">Brooks A</style></author><author><style face="normal" font="default" size="100%">Welch W</style></author><author><style face="normal" font="default" size="100%">Khaldei MG</style></author><author><style face="normal" font="default" size="100%">Hawkins DM</style></author><author><style face="normal" font="default" size="100%">Young SS</style></author><author><style face="normal" font="default" size="100%">Patil K</style></author><author><style face="normal" font="default" size="100%">Howell GW</style></author><author><style face="normal" font="default" size="100%">Ng RT</style></author><author><style face="normal" font="default" size="100%">Chu MT</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">ChemModLab: A web-based cheminromates modeling laboratory</style></title><secondary-title><style face="normal" font="default" size="100%">Cheminformatics</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2012</style></year></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">61-81</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;ChemModLab, written by the ECCR @ NCSU consortium under NIH support, is a toolbox for fitting and assessing quantitative structure-activity relationships (QSARs). Its elements are: a cheminformatic front end used to supply molecular descriptors for use in modeling; a set of methods for fitting models; and methods for validating the resulting model. Compounds may be input as structures from which standard descriptors will be calculated using the freely available cheminformatic front end PowerMV; PowerMV also supports compound visualization. In addition, the user can directly input their own choices of descriptors, so the capability for comparing descriptors is effectively unlimited. The statistical methodologies comprise a comprehensive collection of approaches whose validity and utility have been accepted by experts in the fields. As far as possible, these tools are implemented in open-source software linked into the flexible R platform, giving the user the capability of applying many different QSAR modeling methods in a seamless way. As promising new QSAR methodologies emerge from the statistical and data-mining communities, they will be incorporated in the laboratory. The web site also incorporates links to public-domain data sets that can be used as test cases for proposed new modeling methods. The capabilities of ChemModLab are illustrated using a variety of biological responses, with different modeling methodologies being applied to each. These show clear differences in quality of the fitted QSAR model, and in computational requirements. The laboratory is web-based, and use is free. Researchers with new assay data, a new descriptor set, or a new modeling method may readily build QSAR models and benchmark their results against other findings. Users may also examine the diversity of the molecules identified by a QSAR model. Moreover, users have the choice of placing their data sets in a public area to facilitate communication with other researchers; or can keep them hidden to preserve confidentiality.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Jianqiang C. Wang</style></author><author><style face="normal" font="default" size="100%">S. H. Holan</style></author><author><style face="normal" font="default" size="100%">Balgobin Nandram</style></author><author><style face="normal" font="default" size="100%">Wendy Barboza</style></author><author><style face="normal" font="default" size="100%">Criselda Toto</style></author><author><style face="normal" font="default" size="100%">Edwin Anderson</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Bayesian Approach to Estimating Agricultural Yield Based on Multiple Repeated Surveys</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of Agricultural, Biological, and Environmental Statistics</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bayesian hierarchical model</style></keyword><keyword><style  face="normal" font="default" size="100%">Composite estimation</style></keyword><keyword><style  face="normal" font="default" size="100%">Dynamic model</style></keyword><keyword><style  face="normal" font="default" size="100%">Forecasting Model comparison</style></keyword><keyword><style  face="normal" font="default" size="100%">Prediction</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2011</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 29, 2011</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">84-106</style></pages><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Young SS</style></author><author><style face="normal" font="default" size="100%">Karr Alan</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Deming, data and observational studies. A process out of control and needing fixing</style></title><secondary-title><style face="normal" font="default" size="100%">Significance</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">observational studies</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2011</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">116-120</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Any claim coming from an observational study is most likely to be wrong.? Startling, but true. Coffee causes pancreatic cancer. Type A personality causes heart attacks. Trans-fat is a killer. Women who eat breakfast cereal give birth to more boys. All these claims come from observational studies; yet when the studies are carefully examined, the claimed links appear to be incorrect. What is going wrong? Some have suggested that the scientific method is failing, that nature itself is playing tricks on us. But it is our way of studying nature that is broken and that urgently needs mending, say S. Stanley Young and Alan Karr; and they propose a strategy to fix it.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Nell Sedransk</style></author><author><style face="normal" font="default" size="100%">Lawrence H. Cox</style></author><author><style face="normal" font="default" size="100%">Deborah Nolan</style></author><author><style face="normal" font="default" size="100%">Keith Soper</style></author><author><style face="normal" font="default" size="100%">Cliff Spiegelman</style></author><author><style face="normal" font="default" size="100%">Linda J. Young</style></author><author><style face="normal" font="default" size="100%">Katrina L. Kelner</style></author><author><style face="normal" font="default" size="100%">Robert A. Moffitt</style></author><author><style face="normal" font="default" size="100%">Ani Thakar</style></author><author><style face="normal" font="default" size="100%">Jordan Raddick</style></author><author><style face="normal" font="default" size="100%">Edward J. Ungvarsky</style></author><author><style face="normal" font="default" size="100%">Richard W. Carlson</style></author><author><style face="normal" font="default" size="100%">Rolf Apweiler</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Make research data public? - Not always so simple: A Dialogue for statisticians and science editors</style></title><secondary-title><style face="normal" font="default" size="100%">Statistical Science</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2011</style></year></dates><number><style face="normal" font="default" size="100%">1</style></number><volume><style face="normal" font="default" size="100%">5</style></volume><pages><style face="normal" font="default" size="100%">41-50</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Putting data into the public domain is not the same thing as making those data accessible for intelligent analysis. A distinguished group of editors and experts who were already engaged in one way or another with the issues inherent in making research data public came together with statisticians to initiate a dialogue about policies and practicalities of requiring published research to be accompanied by publication of the research data. This dialogue carried beyond the broad issues of the advisability, the intellectual integrity, the scientific exigencies to the relevance of these issues to statistics as a discipline and the relevance of statistics, from inference to modeling to data exploration, to science and social science policies on these issues.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">S. K. Kinney</style></author><author><style face="normal" font="default" size="100%">J. P. Reiter</style></author><author><style face="normal" font="default" size="100%">AP Reznek</style></author><author><style face="normal" font="default" size="100%">J Miranda</style></author><author><style face="normal" font="default" size="100%">R Jarmin</style></author><author><style face="normal" font="default" size="100%">JM Abowd</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Toward Unrestricted Public Use Business Microdata: The Synthetic Longitudinal Business Database</style></title><secondary-title><style face="normal" font="default" size="100%">International Statistical Review</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2011</style></year></dates><volume><style face="normal" font="default" size="100%">79</style></volume><pages><style face="normal" font="default" size="100%"> 362-384</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><issue><style face="normal" font="default" size="100%">3</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Stephan A. Carr</style></author><author><style face="normal" font="default" size="100%">Nell Sedransk.</style></author><author><style face="normal" font="default" size="100%">Henry Rodriguez</style></author><author><style face="normal" font="default" size="100%">Zivana Tezak</style></author><author><style face="normal" font="default" size="100%">Mehdi Mesri</style></author><author><style face="normal" font="default" size="100%">Daniel C. Liebler</style></author><author><style face="normal" font="default" size="100%">Susan J. Fisher</style></author><author><style face="normal" font="default" size="100%">Paul Tempst</style></author><author><style face="normal" font="default" size="100%">Tara Hiltke</style></author><author><style face="normal" font="default" size="100%">Larry G. Kessler</style></author><author><style face="normal" font="default" size="100%">Christopher R. Kinsinger</style></author><author><style face="normal" font="default" size="100%">Reena Philip</style></author><author><style face="normal" font="default" size="100%">David F. Ransohoff</style></author><author><style face="normal" font="default" size="100%">Steven J. Skates</style></author><author><style face="normal" font="default" size="100%">Fred E. Regnier</style></author><author><style face="normal" font="default" size="100%">N. Leigh Anderson</style></author><author><style face="normal" font="default" size="100%">Elizabeth Mansfield</style></author><author><style face="normal" font="default" size="100%">on behalf of the Workshop Participants</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Analytical Validation of Proteomic-Based Multiplex Assays: A Workshop Report by the NCI-FDA Interagency Oncology Task Force on Molecular Diagnostics</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of Clinical Chemistry</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2010</style></year></dates><volume><style face="normal" font="default" size="100%">56</style></volume><pages><style face="normal" font="default" size="100%">237-243</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Clinical proteomics has the potential to enable the early detection of cancer through the development of multiplex assays that can inform clinical decisions. However, there has been some uncertainty among translational researchers and developers as to the specific analytical measurement criteria needed to validate protein-based multiplex assays. To begin to address the causes of this uncertainty, a day-long workshop titled “Interagency Oncology Task Force Molecular Diagnostics Workshop” was held in which members of the proteomics and regulatory communities discussed many of the analytical evaluation issues that the field should address in development of protein-based multiplex assays for clinical use. This meeting report explores the issues raised at the workshop and details the recommendations that came out of the day’s discussions, such as a workshop summary discussing the analytical evaluation issues that specific proteomic technologies should address when seeking US Food and Drug Administration approval.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Feng J.</style></author><author><style face="normal" font="default" size="100%">Sanil A</style></author><author><style face="normal" font="default" size="100%">Young SS</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">PharmID: Pharmacophore identification using Gibbs sampling</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of Chemical Information and Modeling</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2006</style></year></dates><volume><style face="normal" font="default" size="100%">46</style></volume><pages><style face="normal" font="default" size="100%">1352-1359</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The binding of a small molecule to a protein is inherently a 3D matching problem. As crystal structures are not available for most drug targets, there is a need to be able to infer from bioassay data the key binding features of small molecules and their disposition in space, the pharmacophore. Fingerprints of 3D features and a modification of Gibbs sampling to align a set of known flexible ligands, where all compounds are active, are used to discern possible pharmacophores. A clique detection method is used to map the features back onto the binding conformations. The complete algorithm is described in detail, and it is shown that the method can find common superimposition for several test data sets. The method reproduces answers very close to the crystal structure and literature pharmacophores in the examples presented. The basic algorithm is relatively fast and can easily deal with up to 100 compounds and tens of thousands of conformations. The algorithm is also able to handle multiple binding mode problems, which means it can superimpose molecules within the same data set according to two different sets of binding features. We demonstrate the successful use of this algorithm for multiple binding modes for a set of D2 and D4 ligands.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Bruce E Ankenman</style></author><author><style face="normal" font="default" size="100%">Hui Liu</style></author><author><style face="normal" font="default" size="100%">Alan F. Karr</style></author><author><style face="normal" font="default" size="100%">Jeffrey D. Picka</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Experimental designs for estimating a response surface and variance components</style></title><secondary-title><style face="normal" font="default" size="100%">Technometrics</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2002</style></year></dates><number><style face="normal" font="default" size="100%">1</style></number><volume><style face="normal" font="default" size="100%">44</style></volume><pages><style face="normal" font="default" size="100%">45-54</style></pages><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Julie Rapoport Corina–Maria</style></author><author><style face="normal" font="default" size="100%">Surendra P. Shah</style></author><author><style face="normal" font="default" size="100%">Bruce Ankenman</style></author><author><style face="normal" font="default" size="100%">Alan F. Karr</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Permeability of Cracked Steel Fiber–Reinforced Concrete</style></title><secondary-title><style face="normal" font="default" size="100%">ASCE J. Materials</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2002</style></year></dates><number><style face="normal" font="default" size="100%">4</style></number><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">355–358</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;This research explores the relationship between permeability and crack width in cracked, steel fiber–reinforced concrete. In addition, it inspects the influence of steel fiber reinforcement on concrete permeability. The feedback–controlled splitting tension test (also known as the Brazilian test) is used to induce cracks of up to 500 microns (0.02in) in concrete specimens without reinforcement, and with steel fiber reinforcement volumes of both 0.5% and 1%. The cracks relax after induced cracking. The steel fibers decrease permeability of specimens with relaxed cracks larger than 100 microns. Keywords: permeability, fiber-reinforced concrete, steel fibers 1 NSF Center for Advanced Cement–Based Materials, Northwestern University, 2145 Sheridan Rd., Evanston, IL, 60208–4400, USA 2 Saint Gobain Technical Fabrics, P. Box 728, St. Catharines, Ontario, L2R-6Y3, Canada 3 Department of Industrial Engineering and Management Science, Northwestern University, 2145 Sheridan Rd., Evanston, IL.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>47</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">A. F. Karr</style></author><author><style face="normal" font="default" size="100%">C.-M. Aldea</style></author><author><style face="normal" font="default" size="100%">J. Rapoport</style></author><author><style face="normal" font="default" size="100%">S. P. Shah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Combined effect of cracking and water permeability of fiber-reinforced concrete</style></title><secondary-title><style face="normal" font="default" size="100%">Concrete Under Severe Conditions, Proceedings of the Third International Conference on Concrete Under Severe Conditions</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2001</style></year></dates><pages><style face="normal" font="default" size="100%">71?78</style></pages><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">A. F. Karr</style></author><author><style face="normal" font="default" size="100%">C.-M. Aldea</style></author><author><style face="normal" font="default" size="100%">M. Ghandehari</style></author><author><style face="normal" font="default" size="100%">S. P. Shah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Estimation of water flow through cracked concrete under load</style></title><secondary-title><style face="normal" font="default" size="100%">ACI Materials Journal</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2000</style></year></dates><number><style face="normal" font="default" size="100%">5</style></number><volume><style face="normal" font="default" size="100%">97</style></volume><pages><style face="normal" font="default" size="100%">567?575</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;This research studied the relationship between cracking and water permeability of normal-strength concrete under load and compared the experimental results with theoretical models. A feedback-controlled wedge splitting test was used to generate width-controlled cracks. Speckle interferometry was used to record the cracking history. Water permeability of the loaded specimens was evaluated by a low-pressure water permeability test at the designed crack mouth opening displacements (CMODs). Water permeability results were compared with those previously obtained for unloaded specimens for which cracks were induced by a feedback-controlled splitting tension test. The experimental results indicate that water permeability of cracked material significantly increases with increasing crack width. The flow for the same cracking level is repeatable regardless of the procedure used for inducing the cracks. No direct relationship between water flow and crack length was observed, whereas clear relationships existed between CMOD or crack area and flow characteristics. Experimentally measured flow was compared with theoretical models of flow through cracked rocks with parallel walls and a correction factor accounting for the tortuosity of the crack was determined. Calculated flow through cracks induced by a wedge-splitting test provided an acceptable approximation of the measured flow.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">A. F. Karr</style></author><author><style face="normal" font="default" size="100%">C.-M. Aldea</style></author><author><style face="normal" font="default" size="100%">J.D. Picka</style></author><author><style face="normal" font="default" size="100%">S. P. Shah</style></author><author><style face="normal" font="default" size="100%">S.S. Jaiswal</style></author><author><style face="normal" font="default" size="100%">T. Igusa</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Experimental and statistical study of chloride permeability of cracked high strength concrete</style></title><secondary-title><style face="normal" font="default" size="100%">ASTM Cement, Concrete and Aggregates</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2000</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">2</style></number><volume><style face="normal" font="default" size="100%">22</style></volume><pages><style face="normal" font="default" size="100%">000-000</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Within any cast cylinder of concrete, the coarse aggregate will tend to be inhomogeneously distributed. This variability may arise as a result of segregation caused by gravity or as a result of the wall effect that is caused by the inability of the aggregate to penetrate the walls of the mold. Using methods from image analysis, stereology, and statistics, local estimates of aggregate inhomogeniety are defined that quantify phenomena that have been qualitatively described in the past. These methods involve modification of the two-dimensional images to prepare them for analysis, as well as simple diagnostic statistics for determining the presence of a wall effect. While the techniques presented herein are developed specifically for cast cylinders, they can be generalized to other cast or cored concrete specimens.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>47</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">A. F. Karr</style></author><author><style face="normal" font="default" size="100%">S. P. Shah</style></author><author><style face="normal" font="default" size="100%">S.S. Jaiswal</style></author><author><style face="normal" font="default" size="100%">B.E. Ankenman</style></author><author><style face="normal" font="default" size="100%">J.D. Picka</style></author><author><style face="normal" font="default" size="100%">T. Igusa</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Impact of the interfacial transition zone on the chloride permeability of concrete</style></title><secondary-title><style face="normal" font="default" size="100%">Proc. 12th Engrg. Mechanics Conf</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2000</style></year></dates><pages><style face="normal" font="default" size="100%">1134-1137</style></pages><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">A. F. Karr</style></author><author><style face="normal" font="default" size="100%">S.S. Jaiswal</style></author><author><style face="normal" font="default" size="100%">J.D. Picka</style></author><author><style face="normal" font="default" size="100%">T. Igusa</style></author><author><style face="normal" font="default" size="100%">S. P. Shah</style></author><author><style face="normal" font="default" size="100%">B.E. Ankenman</style></author><author><style face="normal" font="default" size="100%">P. Styer</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Statistical studies of the conductivity of concrete using ASTM C1202?94</style></title><secondary-title><style face="normal" font="default" size="100%">Concrete Science and Engineering</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2000</style></year></dates><volume><style face="normal" font="default" size="100%">2</style></volume><pages><style face="normal" font="default" size="100%">97-105</style></pages><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>47</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">A. F. Karr</style></author><author><style face="normal" font="default" size="100%">C.-M. Aldea</style></author><author><style face="normal" font="default" size="100%">S.S. Jaiswal</style></author><author><style face="normal" font="default" size="100%">B.E. Ankenman</style></author><author><style face="normal" font="default" size="100%">J.D. Picka</style></author><author><style face="normal" font="default" size="100%">T. Igusa</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Water permeability of cracked concrete</style></title><secondary-title><style face="normal" font="default" size="100%">Proc. 12th Engrg. Mechanics Conf</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2000</style></year></dates><pages><style face="normal" font="default" size="100%">1158?1162</style></pages><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Abt, Markus</style></author><author><style face="normal" font="default" size="100%">Welch, William J.</style></author><author><style face="normal" font="default" size="100%">Jerome Sacks</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Design and Analysis for Modeling and Predicting Spatial Contamination</style></title><secondary-title><style face="normal" font="default" size="100%">Mathematical Geology</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">best linear unbiased prediction</style></keyword><keyword><style  face="normal" font="default" size="100%">dioxin contamination</style></keyword><keyword><style  face="normal" font="default" size="100%">Gaussian stochastic process</style></keyword><keyword><style  face="normal" font="default" size="100%">lognormal kriging</style></keyword><keyword><style  face="normal" font="default" size="100%">ordinary kriging</style></keyword><keyword><style  face="normal" font="default" size="100%">spatial statistics</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">1999</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://dx.doi.org/10.1023/A%3A1007504329298</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">1</style></number><publisher><style face="normal" font="default" size="100%">Kluwer Academic Publishers-Plenum Publishers</style></publisher><volume><style face="normal" font="default" size="100%">31</style></volume><pages><style face="normal" font="default" size="100%">1-22</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Sampling and prediction strategies relevant at the planning stage of the cleanup of environmental hazards are discussed. Sampling designs and models are compared using an extensive set of data on dioxin contamination at Piazza Road, Missouri. To meet the assumptions of the statistical model, such data are often transformed by taking logarithms. Predicted values may be required on the untransformed scale, however, and several predictors are also compared. Fairly small designs turn out to be sufficient for model fitting and for predicting. For fitting, taking replicates ensures a positive measurement error variance and smooths the predictor. This is strongly advised for standard predictors. Alternatively, we propose a predictor linear in the untransformed data, with coefficients derived from a model fitted to the logarithms of the data. It performs well on the Piazza Road data, even with no replication.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">A. F. Karr.</style></author><author><style face="normal" font="default" size="100%">C.-M. Aldea</style></author><author><style face="normal" font="default" size="100%">S. P. Shah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of cracking on water and chloride permeability of concrete</style></title><secondary-title><style face="normal" font="default" size="100%">ACSE Journal of Materials in Civil Engineering</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">1999</style></year></dates><number><style face="normal" font="default" size="100%">3</style></number><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">181?187</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The goal of this research was to study the relationship between cracking and concrete permeability and to support accounting for permeability and cracking resistance to other factors besides strength, as criteria to be considered in mix design to achieve a durable concrete. The effect of material composition [normal-strength concrete (NSC) and high-strength concrete (HSC) with two different mix designs] and crack width (ranging from 50 to 400 ?m) on water and chloride permeability were examined. Cracks of designed widths were induced in the concrete specimens using a feedback-controlled splitting tensile test. Chloride permeability of the cracked samples was evaluated using a rapid chloride permeability test and the water permeability of cracked concrete was then evaluated by a low-pressure water permeability test. Uncracked HSC was less water permeable than NSC, as expected, but cracking changed the material behavior in terms of permeability. Both NSC and HSC were affected by cracking, and the water permeability of cracked samples increased with increasing crack width. Among the tested materials, only HSC with a very low water-to-cement ratio chloride permeability was sensitive with respect to cracking. Results indicate that the water permeability is significantly more sensitive than the chloride permeability with respect to the crack widths used in this study.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">A. F. Karr</style></author><author><style face="normal" font="default" size="100%">C.-M. Aldea</style></author><author><style face="normal" font="default" size="100%">S. P. Shah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of microcracking on durability of high strength concrete</style></title><secondary-title><style face="normal" font="default" size="100%">Transportation Research Record</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">1999</style></year></dates><volume><style face="normal" font="default" size="100%">1668</style></volume><pages><style face="normal" font="default" size="100%">86-90</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The relationship between cracking and chloride and water permeability of high-strength concrete (HSC) was studied. Two different mix designs were used: HSC_1 (w/b = 0.31) and HSC_2 (w/b = 0.25). The effects of crack width and sample thickness on permeability were examined. Cracks of designed widths were induced in the concrete specimens using the feedback-controlled splitting tensile test. Chloride permeability of the cracked samples was evaluated by using a rapid chloride permeability test. The water permeability of cracked concrete was then evaluated by a low-pressure water permeability test. Among the materials tested, only high-strength concrete with a very low water-to-cement ratio conductivity is sensitive with respect to cracking. The water permeability of cracked HSC significantly increases with increasing crack width. Among the parameters considered, crack parameters significantly affect water permeability, and there is little thickness effect. The results indicate that the water permeability is significantly more sensitive than conductivity with respect to the crack width used.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">A. F. Karr</style></author><author><style face="normal" font="default" size="100%">C.-M. Aldea</style></author><author><style face="normal" font="default" size="100%">S. P. Shah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Permeability of cracked concrete</style></title><secondary-title><style face="normal" font="default" size="100%">Materials and Structures</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">1999</style></year></dates><volume><style face="normal" font="default" size="100%">32</style></volume><pages><style face="normal" font="default" size="100%">370-376</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The goal of the research presented here was to study the relationship between cracking and water permeability. A feedback-controlled test was used to generate width-controlled cracks. Water permeability was evaluated by a low-pressure water permeability test. The factors chosen for the experimental design were material type (paste, mortar, normal and high strength concrete), thickness of the sample and average width of the induced cracks (ranging from 50 to 350 micrometers). The water permeability test results indicated that the relationships between permeability and material type differ for uncracked and cracked material, and that there was little thickness effect. Permeability of uncracked material decreased from paste, mortar, normal strength concrete (NSC) to high strength concrete (HSC). Water permeability of cracked material significantly increased with increasing crack width. For cracks above 100 microns, NSC showed the highest permeability coefficient, where as mortar showed the lowest one.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>47</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">A. F. Karr</style></author><author><style face="normal" font="default" size="100%">C.-M. Aldea</style></author><author><style face="normal" font="default" size="100%">S. P. Shah</style></author></authors><secondary-authors><author><style face="normal" font="default" size="100%">P. C. Aïtcin</style></author><author><style face="normal" font="default" size="100%">Y. Delagrave</style></author></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Permeability of cracked high strength concrete</style></title><secondary-title><style face="normal" font="default" size="100%">Proceedings of the International Symposium on High Performance and Reactive Powder Concretes</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">1999</style></year></dates><pages><style face="normal" font="default" size="100%">211-219</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The goal of the research presented here was to study the relationship between cracking and water permeability. A feedback-controlled test was used to generate width-controlled cracks. Water permeability was evaluated by a low-pressure water permeability test. The factors chosen for the experimental design were material type (paste, mortar, normal and high strength concrete), thickness of the sample and average width of the induced cracks (ranging from 50 to 350 micrometers). The water permeability test results indicated that the relationships between permeability and material type differ for uncracked and cracked material, and that there was little thickness effect. Permeability of uncracked material decreased from paste, mortar, normal strength concrete (NSC) to high strength concrete (HSC). Water permeability of cracked material significantly increased with increasing crack width. For cracks above 100 microns, NSC showed the highest permeability coefficient, where as mortar showed the lowest one.&lt;/p&gt;
</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Aslett, Robert</style></author><author><style face="normal" font="default" size="100%">Buck, Robert J.</style></author><author><style face="normal" font="default" size="100%">Duvall, Steven G.</style></author><author><style face="normal" font="default" size="100%">Jerome Sacks</style></author><author><style face="normal" font="default" size="100%">Welch, William J.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Circuit optimization via sequential computer experiments: design of an output buffer</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of the Royal Statistical Society: Series C</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Circuit simulator</style></keyword><keyword><style  face="normal" font="default" size="100%">Computer code</style></keyword><keyword><style  face="normal" font="default" size="100%">Computer model</style></keyword><keyword><style  face="normal" font="default" size="100%">Engineering design</style></keyword><keyword><style  face="normal" font="default" size="100%">Parameter design</style></keyword><keyword><style  face="normal" font="default" size="100%">Stochastic process</style></keyword><keyword><style  face="normal" font="default" size="100%">Visualization</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">1998</style></year></dates><volume><style face="normal" font="default" size="100%">47</style></volume><pages><style face="normal" font="default" size="100%">31-48</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;In electrical engineering, circuit designs are now often optimized via circuit simulation computer models. Typically, many response variables characterize the circuit’s performance. Each response is a function of many input variables, including factors that can be set in the engineering design and noise factors representing manufacturing conditions. We describe a modelling approach which is appropriate for the simulator’s deterministic input–output relationships. Non-linearities and interactions are identified without explicit assumptions about the functional form. These models lead to predictors to guide the reduction of the ranges of the designable factors in a sequence of experiments. Ultimately, the predictors are used to optimize the engineering design. We also show how a visualization of the fitted relationships facilitates an understanding of the engineering trade-offs between responses. The example used to demonstrate these methods, the design of a buffer circuit, has multiple targets for the responses, representing different trade-offs between the key performance measures.&lt;/p&gt;
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