13th Annual Conference on Statistical Issues in Clinical Trials: Cluster Randomized Clinical Trials (CRTs): Challenges and Opportunities - CANCELLED

April 29, 2020

Please Note:  This Event has been Canceled

This conference is focused on "Cluster Randomized Clinical Trials (CRTs): Challenges and Opportunities".




7:30 AM - 8:30 AM / Breakfast and Registration

8:30 AM - 4:30 PM / Conference


David Murray, PhD (NIH)

Overview:  Innovations in Design and Analysis of Group or Cluster Randomized Trials

Victor DeGruttola, ScD  (Harvard)

Using network-and individual-level information in design and analysis of clustered trials

Luke J. Keele, PhD (University of Pennsylvania)

Complexities Caused by Noncompliance in Cluster Randomized Trials

James P. Hughes, PhD (University of Washington)

Current issues in the design and analysis of stepped wedge trials


Lawrence H. Moulton, PhD (Johns Hopkins University)

Randomization:  Beyond the Closurization Principle

Ira Longini, PhD (University of Florida)

The ring vaccine trial design for the estimation of vaccine efficacy and effectiveness during infectious disease outbreaks

Deborah J. Donnell, PhD (University of Washington)

Challenges for implementing CRTs: from Hawthorne effect to measurement bias

Weili He, PhD (AbbVie)

Practical considerations in utilizing cluster randomized trials in medical research


Karla Hemming, PhD University of Birmingham
David Murray, PhD National Institutes of Health
Michael Proschan, PhD National Institutes of Health
Jeffrey Roberts, MD US Food and Drug Administration
Alisa Sheilds-Stephens, PhD University of Pennsylvania
Monica Taljaard, PhD Ottowa Hospital Research Institute

Event Type


University of Pennsylvania Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics, Epidemiology and Informatics


National Institute of Statistical Sciences


University of Pennsylvania’s Perelman School of Medicine
Arthur H. Rubenstein Auditorium, Smilow Center for Translational Research
3400 Civic Center Boulevard
United States